Capsaicin-sensitive and -insensitive vagal bronchopulmonary C-fibres in the mouse
نویسندگان
چکیده
منابع مشابه
Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons.
Mechanical stimulation of the somata of cultured neonatal rat dorsal root ganglia (DRG) neurons evoked inward cationic currents that displayed distinct properties between different subsets of cells. The presumptive nociceptor population, defined by capsaicin sensitivity, showed higher thresholds for the induction of an inward current and lower peak currents than other mechanosensitive neurons. ...
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Nicotinic AChR in subclassified capsaicin-sensitive and -insensitive nociceptors of the rat DRG.
Nociceptive cells of the dorsal root ganglion (DRG) were subclassified, in vitro, according to patterns of voltage-activated currents. The distribution and form of nicotinic ACh receptors (nAChRs) were determined. nAChRs were present on both capsaicin-sensitive and -insensitive nociceptors but were not universally present in unmyelinated nociceptors. In contrast, all A delta nociceptors (types ...
متن کاملCCK enhances response to gastric distension by acting on capsaicin-insensitive vagal afferents.
Capsaicin treatment destroys vagal afferent C fibers and markedly attenuates reduction of food intake and induction of hindbrain Fos expression by CCK. However, both anatomical and electrophysiological data indicate that some gastric vagal afferents are not destroyed by capsaicin. Because CCK enhances behavioral and electrophysiological responses to gastric distension in rats and people, we hyp...
متن کاملCapsaicin responses in heat-sensitive and heat-insensitive A-fiber nociceptors.
The recently cloned vanilloid receptor (VR1) is postulated to account for heat and capsaicin sensitivity in unmyelinated afferents. We sought to determine whether heat and capsaicin sensitivity also coexist in myelinated nociceptive afferents. Action potential (AP) activity was recorded from single A-fiber nociceptors that innervated the hairy skin in monkey. Before intradermal injection of cap...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2003
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2003.042028